منابع مشابه
Membrane proteins stick around
You wouldn't call it a long-term relationship, but the interaction between proteins and certain membrane lipids is not just a one-millisecond stand. As Hammond et al. discovered, the proteins remain attached to the lipids longer than researchers expected. The fi ndings explain how these lipids localize their effects. By temporarily hooking up with various proteins, inositol lipids in the plasma...
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The free energy of inserting a protein into a membrane is determined by considering the variation in the spectrum of thermal fluctuations in response to the presence of a rigid inclusion. Both numerically and through a simple analytical approximation, we find that the primary effect of fluctuations is to reduce the effective surface tension, hampering the insertion at low surface tension. Our r...
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In This Issue In This Issue Nuclear proteins get around rotein trafficking between the cytoplasm and the nucleus has been studied extensively; but how do proteins move from one site to another within the nu-cleus? On page 615, Leung and Lamond focus on the intranuclear trafficking of the RNA-binding protein NHPX, and describe an elegant series of experiments that demonstrates the existence of m...
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Recent structural data indicate that the toroidal form is quite common among DNA-binding enzymes. Is this abundance of ring-shaped proteins a coincidence, or does it reflect convergence to a winning quaternary structure?
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2009
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1842iti1